ACTH Level and Sodium-Potassium Ratio in Screening of Primary Canine Hypoadrenocorticism

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ACTH Level and Sodium-Potassium Ratio in Screening of Primary Canine Hypoadrenocorticism

This article describes a primary hypoadrenocorticism (HA) case report in a spayed mix-breeded German shepherd ten years old female dog that had unspecifi c symptoms during a week. The initial suspicious were poisoning and after, renal insuffi ciency, since laboratorial exams demonstrated azotemia. In both cases, the treatment were unsuccessfully. After laboratory exams and blood sodium: potassi...

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Use of the Cortisol‐to‐ACTH Ratio for Diagnosis of Primary Hypoadrenocorticism in Dogs

BACKGROUND The ACTH stimulation test is currently required for definitive diagnosis of hypoadrenocorticism. Increased cost of synthetic ACTH (cosyntropin) has prompted a search for alternative diagnostic methods. OBJECTIVE The purpose of this study was to determine whether a cortisol-to-ACTH ratio (CAR) can be used to differentiate dogs with hypoadrenocorticism from normal dogs and those with...

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Evaluation of the Cortisol‐to‐ACTH Ratio in Dogs with Hypoadrenocorticism, Dogs with Diseases Mimicking Hypoadrenocorticism and in Healthy Dogs

BACKGROUND The adrenocorticotropic hormone (ACTH) stimulation test is the gold standard for diagnosing hypoadrenocorticism (HA) in dogs. However, problems with the availability of synthetic ACTH (tetracosactrin/cosyntropin) and increased costs have prompted the need for alternative methods. OBJECTIVES To prospectively evaluate the cortisol-to-ACTH ratio (CAR) as a screening test for diagnosin...

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Diagnostic efficacy of the leukogram and the chemiluminometric ACTH measurement to diagnose canine hypoadrenocorticism.

BACKGROUND AND OBJECTIVE The gold standard in the diagnosis of canine hypoadrenocorticism (HA) is the adrenocorticotropin (ACTH) response test. As synthetic ACTH (tetracosactide [Synacthen®]) is currently not available in the European Union, the evaluation of other diagnostic tests seemed warranted. The diagnostic efficacy of electrolytes, the leukogram and endogenous ACTH concentrations to dia...

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Canine Hypoadrenocorticism: Pathogenesis and Clinical Features*

dogs.Young, female dogs are predisposed.The most common cause of primary hypoadrenocorticism has been proposed to be immune-mediated destruction of all three layers of the adrenal cortex.This results in mineralocorticoid (aldosterone) and glucocorticosteroid (cortisol) deficiency. Patients typically present with a history of waxing and waning or fulminant gastrointestinal (GI) signs or of acute...

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ژورنال

عنوان ژورنال: International Journal of Veterinary Science and Research

سال: 2017

ISSN: 2640-7604

DOI: 10.17352/ijvsr.000018